Introduction The escalating resistance of microorganisms to antimicrobials poses a significant public health threat. Strategies that use biomarkers to guide antimicrobial therapy—most notably ...

Accelerating protein production with high reproducibility is a key challenge in drug discovery and development. In this webinar, Karthik Rajasekar from Evotec department of Protein Sciences will ...

Pubmed, Science direct and Scielo electronic databases were used to search original articles that are in line with the scope of the study. The descriptors used in the review process were: “extraction” ...

Graphical Abstract: We developed a mechanistic model to simulate purification of a viral-protein complex by cation-exchange chromatography on the “wrong side” of the molecule’s isoelectric point (in a ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

Introduction Sarcopenia, osteoporosis and osteosarcopenia are conditions prevalent in ageing that impair muscle strength and bone density, increasing the risks of fractures, falls, disability and ...

A new study done by scientists in Switzerland and Sweden investigated the use of automated systems to develop multispecific antibodies. Multispecific antibodies (msAbs) are man-made drug modalities ...

Protein samples are essential to advance our understanding of disease pathways and develop new therapeutics. High-quality filtration is needed to protect purity, yield and functionality of target ...

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects in IVD function lead to toxic accumulation of metabolites such as isovaleric ...

Membrane proteins are the gateway to cells and are involved in many critical functions. Each membrane protein is unique, and their complexity makes it difficult to fit into a standardized expression ...

Department of Chemistry & Biochemistry, Florida State University, Tallahassee, Florida 32306, United States Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida 32306, ...